Why would that be Colin?
Suitably flattened off with wet n dry and then primed there shouldn't be any problem!
At least I never had any.
Mind you, I personally prefer to use the Deluxe Ezekote (Ezecote?)
It has several advantages over epoxy:-
One part so no messy mixing
No rushing about if you put too much hardner in😮
Water based so no 'orrible pong and no rock hard brushes😆
just wash 'em out with warm water😉
Dries and can be sanded and primed in 20 - 30 minutes.
That's what I've done with the wooden hulls of my Sea Scout, fish cutter
and PTB and it's worked a treat